This Mac and Cheese Meatloaf Casserole is the ultimate comfort food, combining juicy meatloaf with creamy, cheesy macaroni in one delicious dish. The smoky-sweet barbecue glaze pairs perfectly with the rich mac and cheese, making this a family favorite for weeknight dinners or special gatherings.
Ingredients
For the Meatloaf:
- 2 lbs lean ground beef
- 30 Ritz Crackers, crushed (or use breadcrumbs)
- 2 oz Lipton onion soup mix (1 packet)
- 2 large eggs
- ½ cup ketchup
- ½ cup Sweet Baby Ray’s Hickory & Brown Sugar barbecue sauce
- 1 teaspoon salt
- 1 teaspoon pepper
For the Mac & Cheese Layer:
- 3 cups elbow macaroni noodles
- 2 cups milk (whole milk preferred)
- 10.5 oz condensed cheddar cheese soup (1 can)
- 1 teaspoon salt
- 1 teaspoon pepper
- 1 tablespoon garlic powder
- 1 tablespoon onion powder
- 4 cups shredded cheese blend (mozzarella & cheddar mix)
For the Sauce:
- ½ cup ketchup
- ½ cup Sweet Baby Ray’s barbecue sauce
Instructions
Step 1: Preheat the Oven
- Preheat your oven to 350°F (175°C).
- Grease a 9×13 inch baking dish and set aside.
Step 2: Prepare the Sauce
- In a small mixing bowl, combine ½ cup ketchup and ½ cup barbecue sauce.
- Set aside for later use.
Step 3: Make the Meatloaf
- In a large mixing bowl, add the ground beef.
- Crush the Ritz Crackers and add them to the bowl.
- Add the Lipton onion soup mix and 2 eggs.
- Pour in ½ cup of the ketchup and barbecue sauce mixture.
- Mix everything together until well combined.
- Press the meat mixture evenly into the prepared baking dish.
- Spread the remaining ketchup-barbecue sauce mixture over the top of the meatloaf.
Step 4: Bake the Meatloaf
- Place the dish in the oven and bake for 30 minutes.
- While the meatloaf bakes, prepare the mac and cheese layer.
Step 5: Cook the Macaroni
- Cook the elbow macaroni according to package directions.
- Drain and set aside.
Step 6: Make the Cheese Mixture
- In a large mixing bowl, whisk together milk and condensed cheddar cheese soup until smooth.
- Add salt, pepper, garlic powder, and onion powder.
- Stir in the cooked macaroni and 2 cups of shredded cheese.
- Mix well until fully combined.
Step 7: Assemble and Bake Again
- After the meatloaf has baked for 30 minutes, remove it from the oven.
- Pour the mac and cheese mixture over the top and spread it out evenly.
- Sprinkle the remaining 2 cups of shredded cheese on top.
- Return to the oven and bake for 17-20 minutes, or until the cheese is melted and slightly golden brown.
Step 8: Serve and Enjoy!
- Let the casserole rest for 5 minutes before slicing.
- Serve hot with your favorite side dishes like steamed veggies, garlic bread, or a fresh salad.
Tips & Variations
✔ Make It Spicy: Add ½ teaspoon of cayenne pepper or red pepper flakes for a kick.
✔ Use Different Cheeses: Try Colby Jack, Pepper Jack, or Gouda for a unique flavor twist.
✔ Swap the Meat: Use ground turkey, chicken, or a mix of beef & pork.
✔ Extra Crunch: Top with buttered Panko breadcrumbs or crushed Ritz Crackers before baking.
✔ Make Ahead Friendly: Assemble the casserole up to 24 hours in advance and bake when ready.
Storage & Reheating
Refrigerator:
- Store leftovers in an airtight container for up to 3 days.
Freezer:
- Wrap tightly in plastic wrap and foil, then freeze for up to 3 months.
- Thaw overnight in the fridge before reheating.
Reheating Instructions:
- Oven: Cover with foil and bake at 350°F (175°C) for 15-20 minutes.
- Microwave: Heat in 30-second intervals until warm.
Perfect for Any Occasion
This Mac and Cheese Meatloaf Casserole is a hearty, family-friendly meal that combines two favorites into one dish. Whether it’s for a weeknight dinner, potluck, or special gathering, this casserole is guaranteed to be a hit! Enjoy!